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Moumoujus

SACCHAROMYCES LYSATE EXTRACT.

Insufficient Data / HUMECTANT, SKIN CONDITIONING

Saccharomyces Lysate Extract is a yeast-derived ingredient known for its comprehensive revitalizing effects on the skin. It supports natural cellular renewal and turnover, promoting a smoother texture and more even tone. Furthermore, it acts as an antioxidant and humectant, offering protection from environmental stressors while enhancing hydration.

Summary

Cell Renewal Antioxidant Skin Nourishing Anti-inflammatory Soothing Humectant Skin Microbiome Support Collagen & Hyaluronic Acid Synthesis Support Enhances Ingredient Absorption

Science

Mechanism of Action

This extract functions by stimulating the skin's inherent renewal processes, boosting cell turnover, and reducing the appearance of fine lines. It significantly enhances cellular respiration by increasing oxygen uptake in fibroblasts and leukocytes, which in turn supports the synthesis of vital components like procollagen and hyaluronic acid. Additionally, it provides antioxidant protection against free radicals, nourishes the skin with amino acids, vitamins, and minerals, and exhibits anti-inflammatory and soothing properties. It also contributes to a balanced skin microbiome and acts as a humectant to draw and retain moisture, potentially improving the absorption of other active ingredients.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated up to a 750% increase in oxygen uptake by skin cells.
  2. 02 Shown to boost skin cell turnover activity by up to 25%.
  3. 03 In vitro studies confirm promotion of procollagen and hyaluronic acid synthesis in human dermal fibroblasts.

Transparency

Dusting Analysis

Not commonly dusted

While specific efficacious concentrations are not directly correlated with the impressive in vitro findings, typical cosmetic use ranges are cited between 1% and 5%. The Cosmetic Ingredient Review (CIR) Expert Panel reported a maximum use concentration of 0.067% in their reviewed data, primarily from baby products. The CIR concluded insufficient data for safety at concentrations higher than 0.067%, indicating a regulatory safety concern for typical cosmetic use levels rather than a clear case of dusting for marketing purposes.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a water-soluble yeast extract, it is generally stable in aqueous formulations. While specific stability data for the extract in finished cosmetic products is not detailed, studies on isolated yeast proteins suggest emulsion stability at mildly acidic pH levels (3.5-4.0) due to acid denaturation exposing hydrophobic regions.

Synergies

  • Enhances the absorption of other active ingredients

Safety

Safety Profile

CIR Status
Insufficient data
Max tested
0.067%
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel deemed the available data insufficient to determine the safety of Saccharomyces Lysate Extract under intended cosmetic use conditions. They specifically requested systemic toxicity data (e.g., a 28-day dermal toxicity assay or food use/GRAS/QPS status) and dermal sensitization data to finalize their safety assessment. The highest reported use concentration to the CIR was 0.067% in baby products. No specific SCCS opinion has been issued for this ingredient.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Saccharomyces Lysate Extract presents promising in vitro benefits for skin renewal, hydration, and anti-aging, the Cosmetic Ingredient Review (CIR) has classified available safety data as insufficient, necessitating further testing, especially for concentrations typically used in cosmetics.

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