Science
Mechanism of Action
This dynamic blend operates on multiple cellular levels. The Saccharomyces/Rice Ferment Filtrate component enhances skin hydration by increasing Aquaglyceroporin-3 (AQP3) protein content and promoting the production of other moisturizing and barrier-related proteins. It nurtures the skin's microflora, stimulates collagen synthesis for improved elasticity, and provides potent antioxidant defense against environmental stressors. Rich in vital nutrients like vitamins, minerals, amino acids, and peptides, it boosts cell vitality, regulates sebum, and inhibits melanin production. Complementing this, Licorice Root Extract delivers anti-inflammatory and antimicrobial benefits through compounds like glycyrrhizin and glabridin. Glabridin specifically reduces UV-induced hyperpigmentation by suppressing tyrosinase activity—the enzyme crucial for melanin synthesis—and neutralizing reactive oxygen species. Additionally, liquiritin within the extract aids in dispersing existing melanin to fade discoloration.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Red rice ferment filtrate, at concentrations of 1.25% and 3%, significantly elevated AQP3 protein levels in keratinocytes. The 1.25% concentration demonstrated superior improvement in skin water content compared to 3%, alongside enhancing various moisturizing and barrier-related proteins and genes.
- 02 Rice Berry Ferment Filtrate (Lactobacillus/Oryza Sativa) at 2.0% to 5.0% (with 5% recommended) enhanced barrier function, boosted skin hydration, and exhibited anti-inflammatory and antioxidant properties to combat oxidative stress.
- 03 Saccharomyces/Rice Ferment Filtrate (RiFerm®) demonstrated robust anti-oxidant and anti-wrinkle activities in vitro, and delivered significant improvements in skin hydration and elasticity in vivo.
- 04 A serum formulation containing 20% licorice root extract yielded optimal facial brightening results.
- 05 Topical application of 0.5% glabridin, a key component of licorice root extract, effectively inhibited UVB-induced pigmentation in guinea pigs.
Transparency
Dusting Analysis
No specific data regarding dusting found in the provided research.
The Formula
Formulation
Stability
For optimal stability of the rice ferment component, temperatures exceeding 40°C should be avoided. Long-term storage is best achieved through refrigeration. The ingredient should be stored in a cool, dark, and dry environment. The ideal pH range for formulations containing this blend is between 3.0 and 7.0, with licorice root extract itself having a pH range of 4.0-4.7.
Safety
Safety Profile
The CIR Expert Panel found 'insufficient data' for the blend as a whole. While Licorice Root Extract is generally considered safe, the Saccharomyces Ferment Filtrate component received a conditional safety status, requiring sufficient dermal sensitization data and GRAS/QPS status for the specific yeast species used. Therefore, for this specific blend, comprehensive safety data is still pending for a definitive 'safe as used' conclusion.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multifaceted blend offers significant benefits for hydration, barrier enhancement, antioxidant protection, and skin brightening, making it a valuable addition to formulations targeting diverse skin concerns.
Related
Similar Ingredients
Finding similar ingredients…