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SACCHAROMYCES/FLUORIDE FERMENT.

Insufficient Data / SKIN CONDITIONING

SACCHAROMYCES/FLUORIDE FERMENT is designed to harness the well-documented benefits of Saccharomyces ferment, such as enhancing skin hydration, reinforcing barrier function, and providing antioxidant support. However, specific clinical data for this particular fluoride-inclusive ferment is absent, and available research suggests fluoride may inhibit fermentation processes, raising questions about its functional contribution.

Natural deodorant Antioxidant Moisturizing Skin-soothing Skin-brightening Anti-aging

Science

The Saccharomyces ferment component functions by delivering vital nutrients and antioxidants to the skin, which can mitigate inflammation, stimulate collagen synthesis, and improve skin elasticity. Its composition, rich in polysaccharides, peptides, essential minerals, amino acids (including glycine and proline), beta-glucan, and vitamins, works to nourish, moisturize, and protect the skin. Amino acids are known to activate aquaporin 3 (AQP3) expression, enhancing the skin's capacity for water absorption, while polysaccharides support tight junction protein synthesis, bolstering the skin's barrier. The precise mechanism or benefit of the fluoride component within this ferment remains undefined by research.


Research

Insufficient-data confidence
Effective range 0.1–5%
Optimal

5%

Key findings

  1. 01 Continuous application of a spray containing 5% Saccharomyces boulardii fermented product filtrate over four weeks significantly reduced trans-epidermal water loss (TEWL) by an average of 37.2% and increased stratum corneum hydration by 62.5%.
  2. 02 Topical application of a dried Saccharomyces Cerevisiae ferment reduced histamine-induced skin inflammation, decreased time to maximum blood perfusion, and accelerated inflammation resolution in a placebo-controlled study with 12 volunteers.
  3. 03 Saccharomyces Ferment Filtrate is generally recommended for leave-on products at concentrations between 0.1% and 5% for its benefits in improving skin health, providing antioxidants, reducing inflammation, boosting collagen, and refining skin texture.

Transparency

Commonly dusted

While Saccharomyces ferments are well-researched for their skin benefits, the specific combination as 'SACCHAROMYCES/FLUORIDE FERMENT' lacks dedicated efficacy and safety data. Research indicates fluoride can inhibit fermentation, suggesting its inclusion in this specific form may not confer additional benefits and could potentially compromise the primary ferment activity, raising concerns about its functional rationale.


The Formula

Solubility
Water
Optimal pH 2.5 – 9.5
0 7 14

Stability

Saccharomyces Ferment exhibits stability across a broad pH range of 2.5 to 9.5. For optimal formulation stability, it is advised to incorporate this ingredient during the cooling phase. Storage between 16°C and 32°C, with an optimal range of 23-25°C, is recommended for maximizing shelf life.


Safety

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has issued an 'Insufficient Data Announcement' for yeast-derived ingredients, requesting further safety data. While Saccharomyces cerevisiae is generally recognized as safe (GRAS) by the FDA for food use up to 5%, specific safety data for 'SACCHAROMYCES/FLUORIDE FERMENT' combining both components is unavailable. Notably, fluoride has been observed to inhibit fermentation, suggesting potential implications for the efficacy and safety profile of this combined ingredient.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While Saccharomyces ferments generally offer valuable skin benefits, the specific ingredient 'SACCHAROMYCES/FLUORIDE FERMENT' lacks dedicated safety and efficacy data, particularly concerning the fluoride component, which research suggests may inhibit fermentation.


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