Science
Mechanism of Action
Saccharomyces Ferment Lysate Filtrate acts multi-dimensionally to enhance skin vitality. It functions as a skin conditioning agent, providing a suite of benefits including anti-aging, intense moisturization, and comprehensive repair. The ingredient exhibits anti-inflammatory and antioxidant capabilities, fostering the generation of new cells and facilitating the shedding of old skin cells. It actively supports the skin's inherent protective and reparative processes, renewing keratinocytes and aiding in recovery from UV-induced damage. By stimulating the skin's immune system, it bolsters dermal resistance. Rich in human-like cytokines and growth factors, it boosts cellular oxygen uptake and stimulates soluble elastin production by fibroblasts. It delivers crucial nutrients such as amino acids (e.g., glycine, proline), beta-glucan, minerals, and vitamins, which collectively reduce inflammation, promote collagen synthesis, and enhance skin elasticity and texture, visibly diminishing fine lines and wrinkles. Furthermore, it stimulates skin regeneration, helps to rebuild the protective barrier, and functions as a humectant by drawing in moisture and improving retention via natural moisturizing factors (NMFs) and heightened aquaporin 3 (AQP3) expression. The fermentation process breaks down yeast components into smaller, more bioavailable forms, optimizing skin penetration and enhancing the absorption of other active ingredients. It can also help regulate excess sebum to achieve a balanced oil-water ratio in the skin.
Research
Clinical Evidence
Medium confidence5%
Key findings
- 01 Continuous use of a spray containing 5% Saccharomyces boulardii fermented product filtrate (a related ingredient) for four weeks resulted in an average reduction of trans-epidermal water loss (TEWL) by 37.2% and stratum corneum hydration increased by 62.5%.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability is observed within a pH range of 3.0-5.0 (for a related ingredient, FSS Saccharomyces Ferment) and it remains stable up to 60°C. For best results, incorporate during the cooling phase of formulation and avoid freezing.
Conflicts
- Direct acids (potential for over-exfoliation when combined with related products)
- Physical exfoliators (potential for over-exfoliation when combined with related products)
Safety
Safety Profile
The CIR Expert Panel concluded that data were insufficient to determine the safety of highly similar ingredients like 'Saccharomyces Lysate Extract Filtrate' and 'Saccharomyces Lysate Filtrate'. However, a proprietary blend containing 24.5% Saccharomyces Ferment Lysate Filtrate tested negatively in a mammalian cell gene mutation assay. Generally, it is considered a safe cosmetic ingredient with no reported side effects and is suitable for all skin types. Its parent organism, Saccharomyces cerevisiae, holds Generally Recognized As Safe (GRAS) status for food flavoring at concentrations up to 5%. No specific SCCS opinion or FDA cosmetic regulatory status is available for this exact ingredient.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multi-functional fermented ingredient is a valuable addition to skincare formulations, offering extensive hydrating, repairing, and anti-aging benefits with a low risk of irritation for all skin types, despite a current lack of direct CIR safety determination.
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