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Moumoujus

RIBOFLAVIN TETRABUTYRATE.

Insufficient Data CAS 752-56-7 / SKIN CONDITIONING

Riboflavin Tetrabutyrate is a lipophilic derivative of Vitamin B2 (Riboflavin), engineered for enhanced skin penetration and stability. It functions as a potent antioxidant, actively neutralizing free radicals to protect skin cells and support rejuvenation. This ingredient aims to improve cellular defense and overall skin health.

Summary

antioxidant skin conditioning free radical scavenger anti-aging

Science

Mechanism of Action

This advanced derivative of Vitamin B2 leverages its enhanced lipophilicity to achieve superior penetration into the skin. Once absorbed, Riboflavin Tetrabutyrate acts as a powerful antioxidant, effectively neutralizing harmful free radicals and mitigating lipid peroxidation to protect cellular integrity. It plays a crucial role in redox reactions and supports the regeneration of glutathione, a vital endogenous antioxidant, thereby bolstering the skin's natural defense mechanisms and promoting a resilient complexion.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Riboflavin Tetrabutyrate exhibits enhanced stability compared to free riboflavin. However, its parent compound, Riboflavin, is highly sensitive to light and unstable in alkaline solutions. While neutral and acidic solutions of Riboflavin show stability around pH 5-6 (approximately 3% decomposition per month at 27 °C), solutions of Riboflavin Tetrabutyrate are generally recommended for immediate use to ensure peak efficacy and should be protected from light.

Conflicts

  • strong oxidizing agents
  • reducing agents
  • bases
  • calcium
  • metallic salts
  • light (especially in alkaline solutions)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Riboflavin Tetrabutyrate has not been specifically reviewed by the Cosmetic Ingredient Review (CIR) Expert Panel or the Scientific Committee on Consumer Safety (SCCS). While its parent compound, Riboflavin (Vitamin B2), is recognized as Generally Recognized As Safe (GRAS) by the FDA for food applications, the specific FDA status for Riboflavin Tetrabutyrate as a cosmetic ingredient is not explicitly stated. General handling guidelines advise avoiding inhalation of dust and direct contact with skin and eyes.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Riboflavin Tetrabutyrate presents a promising mechanism as a potent, penetrating antioxidant, there is currently insufficient specific data regarding its clinical efficacy, optimal concentration, and detailed skin compatibility (irritancy, comedogenicity) to provide a definitive assessment for cosmetic applications.

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