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RETINYL TALLATE.

Insufficient Data CAS - / SKIN CONDITIONING

Retinyl Tallate is a specialized Vitamin A derivative functioning as a skin conditioning agent. This retinyl ester undergoes a multi-step conversion within the skin to its active form, retinoic acid, offering comprehensive anti-aging benefits with a potentially lower irritation profile. It supports skin elasticity, cell renewal, and collagen synthesis.

Skin conditioning Anti-aging Enhances cell renewal Stimulates collagen production Improves skin elasticity

Science

As a retinyl ester, Retinyl Tallate penetrates the skin and is sequentially metabolized. Esterase enzymes convert it to retinol, which is then oxidized to retinal, and ultimately to retinoic acid—the bioactive form of Vitamin A. This indirect pathway to retinoic acid is theorized to mitigate potential skin irritation often associated with more direct retinoids, while effectively promoting cellular turnover, enhancing skin elasticity, inhibiting collagen degradation, and stimulating new collagen production. It primarily addresses signs of aging, dryness, and light-stressed skin.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Information regarding the 'dusting' potential or specific thresholds for Retinyl Tallate is not available in the current research data.


The Formula

Solubility
Oil
Optimal pH 5 – 7
0 7 14

Stability

Retinyl Tallate, while generally more stable than pure retinol due to its ester form, remains susceptible to degradation from light, air, oxidation, heat, and trace metals. Optimal stability is maintained in formulations stored below 4°C, ideally under an inert gas (e.g., argon, nitrogen), and with the inclusion of antioxidants like butylated hydroxytoluene (BHT) or tocopherol. Airless packaging systems are also recommended to minimize exposure and preserve efficacy.

Conflicts

  • strong chemical exfoliants (e.g., alpha hydroxy acids, beta hydroxy acids)
  • benzoyl peroxide
  • Vitamin C (L-ascorbic acid) - caution advised, as concurrent use might lead to instability without careful formulation design.

Safety

CIR Status
Insufficient data
Sensitization risk Unknown

The CIR Expert Panel considered Retinyl Tallate for review in 2012 but has not issued a specific safety assessment or final conclusion. The SCCS opinions (2016, 2021) on Vitamin A derivatives specifically evaluated retinol, retinyl acetate, and retinyl palmitate, concluding safety at certain retinol equivalent concentrations (0.05% RE in body lotion, 0.3% RE for other leave-on/rinse-off products), but explicitly excluded other derivatives like Retinyl Tallate due to a lack of specific data. As a cosmetic ingredient, Retinyl Tallate does not require pre-market approval by the FDA, unless it is a color additive.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While Retinyl Tallate presents as a promising, potentially gentler retinoid derivative for anti-aging and skin conditioning, comprehensive safety and efficacy data specific to this ingredient are currently insufficient for a definitive rating.


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