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RETINYL SOYATE.

Insufficient Data CAS - / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Retinyl Soyate is a retinyl ester, a derivative of Vitamin A, synthesized by esterifying retinol with fatty acids from soy. It functions as a precursor, designed to be metabolized in the skin into retinol and subsequently into the biologically active retinoic acid, aiming to deliver retinoid benefits.

Skin conditioning Antioxidant

Science

Upon application, Retinyl Soyate is anticipated to undergo enzymatic hydrolysis by esterases within the skin, converting it into retinol. Retinol then follows a metabolic pathway, first oxidizing to retinal, and then to retinoic acid. Retinoic acid is the form of Vitamin A that binds to nuclear receptors, initiating cellular processes responsible for its dermatological effects, such as influencing cell proliferation and differentiation.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

No specific data available to suggest Retinyl Soyate is commonly dusted or has known dusting thresholds.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As a retinoid, Retinyl Soyate is inherently susceptible to degradation by heat, light, moisture, and air, similar to other retinyl esters. This susceptibility suggests a need for protective formulation strategies to maintain its stability and efficacy.

Synergies

  • Antioxidants (e.g., tocopherol, BHT, BHA) to mitigate oxidation
  • Encapsulation technologies (e.g., cyclodextrins, liposomes) to enhance stability and controlled release

Conflicts

  • Oxidizing agents
  • Exposure to high heat, direct light, or air which can accelerate degradation

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Retinyl Soyate has not undergone a dedicated safety review by the CIR Expert Panel, though it was considered for inclusion in a re-review of other retinyl esters. The Panel expected it to metabolize to retinol. While specific maximum concentration limits for Retinyl Soyate are not established, the SCCS provides guidance for 'retinol equivalent' concentrations for other retinoids: 0.05% in body lotions and 0.3% in other leave-on and rinse-off products. It is important to note that retinoic acid is prohibited in cosmetic products within the EU.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

Retinyl Soyate theoretically offers retinoid benefits through its conversion to active Vitamin A forms, but lacks specific clinical studies to validate its direct efficacy and safety profile, requiring reliance on general retinoid understanding.


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