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Moumoujus

R-(OLIGOPEPTIDE-126 SH-POLYPEPTIDE-2).

Insufficient Data / ANTIOXIDANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

R-(OLIGOPEPTIDE-126 SH-POLYPEPTIDE-2) is an engineered fusion peptide, intricately combining the antioxidant capabilities of Thioredoxin (SH-POLYPEPTIDE-2) with the potent signaling properties of an oligopeptide. This advanced ingredient is designed to activate intrinsic skin repair mechanisms, combat oxidative stress, and enhance the skin's structural integrity for improved appearance.

Summary

Antioxidant Skin Conditioning Emollient Collagen Boosting Elastin Boosting Hyaluronic Acid Boosting Skin Regeneration Wrinkle Reduction Complexion Improvement

Science

Mechanism of Action

This fusion peptide operates through a dual-action mechanism within the skin. Its SH-POLYPEPTIDE-2 component, identified as Thioredoxin (TRX), acts as a powerful antioxidant, actively neutralizing free radicals to protect cells from environmental damage. TRX is also associated with improvements in overall skin complexion and a reduction in the visible signs of wrinkles. Simultaneously, the oligopeptide segment functions as a signaling molecule, initiating and upregulating the skin's endogenous repair pathways. This stimulation leads to enhanced collagen production, improved skin elasticity, and an increased biosynthesis of vital extracellular matrix components, including hyaluronic acid, thereby contributing to a more youthful and resilient skin architecture.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a peptide, R-(OLIGOPEPTIDE-126 SH-POLYPEPTIDE-2) is generally susceptible to degradation by extreme pH conditions, elevated temperatures, and proteolytic enzymes. Specific optimal pH or precise stability parameters for this particular fusion peptide are currently undefined.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No dedicated safety assessments from regulatory bodies such as CIR, SCCS, or FDA for R-(OLIGOPEPTIDE-126 SH-POLYPEPTIDE-2) have been identified. While its Thioredoxin component (SH-POLYPEPTIDE-2) is not listed on prominent restriction lists, a general cautionary note exists for growth factor-mimicking peptides, citing a potential correlation with tumorigenesis or progression. This is a broad consideration for growth factors as a class and not a specific finding for this particular fusion peptide.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

R-(OLIGOPEPTIDE-126 SH-POLYPEPTIDE-2) presents a promising dual mechanism for skin protection and rejuvenation, yet comprehensive clinical studies and specific safety assessments are currently lacking for a definitive evaluation.

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