Science
Mechanism of Action
This extract primarily acts as an antioxidant by reducing Reactive Oxygen Species (ROS) induced by various stressors, such as H2O2 or LPS, within human skin keratinocytes. Its mechanism involves upregulating antioxidant regulatory enzymes, specifically CAT and SOD1 genes, while simultaneously decreasing the expression of the pro-oxidant regulator NOS2. Beyond its free radical scavenging properties, it also contributes to epidermal health through keratolytic, moisturizing, and skin conditioning actions.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The key antioxidant compounds found in sour cherries, anthocyanins, are inherently water-soluble, which supports the extract's hydrosoluble nature and its stability in aqueous formulations.
Conflicts
- The addition of cherry and sweet cherry fruit extracts to a formulation has been observed to lead to a decrease in its overall viscosity.
Safety
Safety Profile
Reported side effects and adverse reactions are uncommon. The EWG Skin Deep database rates Prunus Cerasus Extract as a low concern for potential risks including cancer, allergies & immunotoxicity, and developmental & reproductive toxicity. While not formally reviewed by CIR, the FDA acknowledges related cherry pit extracts as flavoring agents, and Prunus Cerasus Fruit Extract is broadly used in cosmetics and as a dietary supplement.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Prunus Cerasus Extract is a valuable ingredient due to its robust antioxidant properties, broad compatibility across all skin types, and its multifaceted benefits, including effective moisturizing, conditioning, and anti-aging effects.
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