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PROPYL VALERATE.

Avoid CAS 141-06-0 / PERFUMING

Propyl valerate is a short-chain fatty acid ester primarily utilized as a flavor and fragrance agent. Its metabolic derivative, valeric acid, is known to activate the FFAR3 receptor, which plays a role in regulating metabolic processes and inflammatory responses.

fragrance ingredient

Science

As a short-chain fatty acid ester, propyl valerate's derivative, valeric acid, functions as an activator for the free fatty acid receptor 3 (FFAR3 or GPR41). This receptor is integral to modulating various biological processes, including metabolism, inflammation, and hormone homeostasis, which could theoretically impact skin health.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient is susceptible to degradation in the presence of strong oxidizing agents, strong acids, and strong bases. As a flammable liquid, it requires storage conditions that avoid heat, hot surfaces, sparks, open flames, and other ignition sources.

Conflicts

  • strong oxidizing agents
  • strong acids
  • strong bases
  • heat
  • ignition sources

Safety

CIR Status
Not reviewed
Sensitization risk High

Propyl valerate's primary applications are in flavor and fragrance. It carries an irritant classification (Xi), indicating potential irritation to the eyes, respiratory system, and skin. Standard safety protocols recommend avoiding direct contact with skin and eyes. Currently, there are no dedicated safety evaluations from regulatory bodies like CIR or SCCS for its use in cosmetics, nor specific FDA guidelines for skincare applications.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its classification as an irritant and the absence of specific safety assessments for cosmetic application, this ingredient is not recommended for skincare formulations.


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