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Moumoujus

PROPYL METHACRYLATE.

Avoid CAS 2210-28-8 / FILM FORMING

Propyl methacrylate is a monomer belonging to the methacrylate ester family, primarily utilized in specialized nail enhancement products for its ability to build and lengthen nails. This compound is associated with significant potential for skin and serious eye irritation, and may also induce respiratory irritation.

Summary

Science

Mechanism of Action

No documented mechanism for beneficial action on skin. Its primary utility involves polymerization to form a solid matrix, contributing to the structure and extension of nails.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Propyl methacrylate functions as a reactive monomer in specific applications rather than a cosmetic filler, and is therefore not typically a 'dusted' ingredient.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Methacrylate esters generally exhibit poor resistance to various chemicals, owing to their ester groups being prone to hydrolysis. Furthermore, propyl methacrylate is characterized as a flammable liquid and vapor, necessitating careful handling.

Conflicts

  • strong organic solvents (when polymerized)
  • extreme pH conditions (when polymerized, due to hydrolysis)
  • direct skin contact (due to high sensitizing potential of the monomer)

Safety

Safety Profile

CIR Status
Safe with restrictions
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that methacrylate ester monomers are safe for use in nail enhancement products, provided that application protocols strictly enforce avoiding skin contact due to their inherent sensitizing potential. n-Propyl methacrylate specifically poses risks including skin irritation, serious eye irritation, and potential respiratory irritation, and is categorized as a flammable liquid and vapor. It is crucial to distinguish this monomer from Polymethyl methacrylate (PMMA), which is a polymer of *methyl* methacrylate, not propyl methacrylate, and is approved by the FDA for certain medical devices and recognized as safe for cosmetic use by CIR based on this approval.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Propyl methacrylate is highly discouraged for skincare formulations due to its documented high irritancy and significant sensitizing potential, with its recognized use strictly confined to nail enhancement products under stringent conditions to prevent skin contact.

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