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PROPIONALDEHYDE.

Avoid CAS 123-38-6 / PERFUMING

Propionaldehyde is an organic aldehyde primarily utilized for its aromatic properties in consumer products. Characterized by high reactivity and significant irritancy potential, its topical application requires considerable caution.

fragrance ingredient

Science

Its primary function in formulations is to impart fragrance. While some research indicates a broader biological activity concerning intercellular communication, this effect has not been established as beneficial for skin health in a cosmetic context.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Propionaldehyde is a highly reactive substance prone to oxidation when exposed to oxygen, necessitating storage under inert gases. Contamination or elevated temperatures can induce hazardous polymerization.

Conflicts

  • oxidizers
  • strong bases
  • strong reducing agents
  • methyl methacrylate

Safety

CIR Status
Not reviewed
Sensitization risk High

The Cosmetic Ingredient Review (CIR) has not specifically evaluated Propionaldehyde for safety in cosmetics. The EU SCCS has not published an opinion on it, though similar aldehydes have been banned due to CMR classification. The U.S. FDA previously approved it as a food flavoring but no longer lists it under relevant regulations for direct addition. Given its high irritancy potential, significant caution is advised for topical use.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its high irritancy potential, lack of beneficial skincare mechanisms, unreviewed safety profile by key regulatory bodies, and formulation challenges, Propionaldehyde is not recommended for precision skincare.


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