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Moumoujus

PROPANE TRICARBOXYLIC ACID.

Avoid CAS 99-14-9 / 51750-56-2 / BUFFERING, CHELATING

Propane Tricarboxylic Acid, also known as tricarballylic acid, functions primarily as a buffering and chelating agent in cosmetic formulations. Its biochemical recognition stems from its activity as an inhibitor of the aconitase enzyme.

Summary

buffering agent chelating agent

Science

Mechanism of Action

Within a skincare product, Propane Tricarboxylic Acid's carboxylic acid groups enable it to regulate the formulation's pH, acting as a buffering agent. Additionally, it can chelate, or bind to, metal ions, thereby stabilizing ingredients and preserving product integrity against metallic contamination or oxidation.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

GHS classification explicitly states that Propane Tricarboxylic Acid 'Causes skin irritation' and 'Causes serious eye irritation.' The European Chemicals Agency (ECHA) further notes potential respiratory irritation. While listed in various inventories such as AICIS and the NZ EPA, its documented irritancy presents a significant concern for cosmetic application.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Given the high risk of skin and eye irritation, coupled with a lack of specific direct skin benefits, Propane Tricarboxylic Acid is deemed unsuitable for precision skincare formulations.

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