Science
Mechanism of Action
This ingredient operates by enhancing the skin barrier through the filling of intercellular gaps within corneocyte clusters, which effectively improves skin hydration and significantly reduces transepidermal water loss. In formulations, it acts as a surfactant and emulsifying agent, lowering interfacial tension to promote emulsion stability and homogeneity.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that PPG-3-Myreth-3, along with other propylene glycols containing 3 or more propylene oxide units, is safe for use in cosmetic formulations provided it is formulated to be nonirritating. It is important to note that the ethoxylation reaction involved in its production may result in trace residues of ethylene oxide and 1,4-dioxane, both identified as carcinogenic. While product labels typically do not disclose these residues, a related compound, PPG-3 Benzyl Ether Myristate, has a low hazard rating (EWG score of 1). However, another related compound, PPG-3 Myristyl Ether, has been reported to cause serious eye irritation in 21.7% of instances.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PPG-3-Myreth-3 is a valuable ingredient for enhancing skin hydration and barrier function, although specific data on its irritancy and comedogenicity for direct application are unknown, and potential manufacturing residues warrant consideration for precision formulations.
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References
Sources