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POTASSIUM HYDROXIDE.

Valuable CAS 1310-58-3 / BUFFERING

Potassium Hydroxide is a strong alkaline compound primarily utilized in skincare formulations to precisely control and stabilize pH. Beyond its crucial buffering role, it also acts as a potent keratolytic agent, facilitating the breakdown and removal of dead skin cells at higher, regulated concentrations.

pH adjuster Buffering Keratolytic Emulsifier

Science

Potassium hydroxide profoundly impacts the skin through several mechanisms. Its primary action involves saponification, where hydroxide ions convert fatty acids in cell membranes into soap and glycerol, thereby compromising the skin's lipid barrier. It further denatures structural proteins like keratin and collagen, contributing to skin weakening and cellular breakdown. As a hygroscopic substance, it draws water from cells, inducing dehydration. In cosmetic applications, these properties make it an effective keratolytic, softening keratin for exfoliation, and a critical pH adjuster to ensure product stability and optimal ingredient function.


Research

Medium confidence
Effective range 10–15%
Optimal

10%


Transparency

Not commonly dusted

Potassium hydroxide is a fundamental functional ingredient, primarily serving as a pH adjuster. Its inclusion is driven by formulation necessity rather than 'dusting' or marketing claims without purpose. Its activity as a keratolytic also ensures a clear functional role when used at higher, regulated concentrations.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a strong alkali, potassium hydroxide is highly effective in adjusting and stabilizing the pH of cosmetic products, which is essential for maintaining product integrity, active ingredient efficacy, and skin compatibility. It dissolves readily in water, alcohol, and glycerol but is insoluble in oils and non-polar solvents.

Conflicts

  • Acids (due to its strong alkaline nature, leading to neutralization)
  • Oils and non-polar solvents (due to insolubility)

Safety

CIR Status
Safe with restrictions
Max tested
7%
Sensitization risk High

The CIR Expert Panel deems inorganic hydroxides, including potassium hydroxide, safe when used as directed in hair straighteners and depilatories, minimizing skin contact. The SCCS restricts its use as a callosity softener/remover to 1.5% and up to 5% in nail cuticle solvents. For hair straighteners, it's limited to 2% (general) and 4.5% (professional), with pH adjuster uses up to pH 12.7 in depilatories and pH 11 for other applications. Notably, concentrations of 2% and higher are corrosive, while solutions between 0.5% and 2% can cause skin and eye irritation. A reported use in a leave-on body and hand product reached up to 7%.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Low

Our Assessment

Valuable

Potassium Hydroxide is a valuable ingredient, indispensable for precise pH stabilization across diverse formulations, and effective as a keratolytic agent at carefully controlled, higher concentrations, provided strict adherence to safety guidelines.


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