Science
Mechanism of Action
As a member of the polyurethane family, POLYURETHANE-70 predominantly acts as a film-forming agent, creating a thin, flexible layer on the skin surface. Research on general polyurethanes, particularly in wound care, suggests a potential role in supporting cellular organization, such as fibroblasts, and contributing to extracellular matrix deposition, which could positively influence re-epithelialization and scar appearance. Additionally, it can function as a structural 'bridge' within hydrogel formulations, thereby improving elasticity, strength, and adhesion without causing irritation.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
No data available in the provided research suggests that POLYURETHANE-70 is commonly 'dusted' or associated with specific concentration thresholds for adverse effects related to dusting.
The Formula
Formulation
Stability
POLYURETHANE-70 is dispersible in water. The hydrolytic stability of polyurethanes is influenced by factors including temperature, steric hindrance, water absorption, and pH. Polyether polyurethanes generally exhibit enhanced resistance to hydrolysis from water or alkaline conditions, making them suitable for moisture-rich or mildly basic environments. Optimal stability is observed when stored and handled according to prescribed guidelines, with extreme temperatures being avoided.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that polyurethanes, including Polyurethane-70, are safe when formulated to be non-sensitizing and used within established practices and concentrations. While Polyurethane-70 was not extensively used in cosmetics at the time of the 2017 assessment, its anticipated future applications are expected to mirror those of other polyurethanes. A key safety consideration lies in the potential presence of residual diisocyanate monomers, which are precursors to polyurethanes. These monomers have been linked to irritant/allergic contact dermatitis and other adverse reactions. However, modern manufacturing processes are engineered to minimize the levels of these residual monomers, thus reducing the associated risks.
Your Skin
Skin Compatibility
Our Assessment
Verdict
POLYURETHANE-70 is a valuable film-forming ingredient, deemed safe for cosmetic use by the CIR when properly formulated, offering textural benefits and potential skin support despite limited specific clinical data.
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References
Sources