Science
Mechanism of Action
As a film-forming agent, POLYURETHANE-64 deposits an elastic, non-tacky layer upon application to the skin. This breathable film physically helps to seal in moisture, thereby reducing trans-epidermal water loss, diminishing skin roughness, and creating a shield against various environmental factors.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
POLYURETHANE-64 exhibits robust stability within a pH range of 4.0 to 9.0. However, exposure to strongly acidic conditions (pH 1-3) can induce hydrolysis of its urethane linkages. Formulators should exercise caution when attempting to significantly lower the pH of waterborne dispersions, as this can destabilize the ingredient.
Conflicts
- Combining solutions containing multiple sensitizers, such as methylisothiazolinone (MI), particularly when POLYURETHANE-64 is supplied as an emulsion with such components, should be avoided to prevent reaching problematic concentrations.
- Strongly acidic environments (pH 1-3) may compromise the structural integrity of urethane linkages.
- Drastically lowering the pH of waterborne POLYURETHANE-64 dispersions risks destabilization.
Safety
Safety Profile
The CIR Expert Panel has deemed POLYURETHANE-64 safe for use in cosmetic formulations, provided it is formulated to be non-sensitizing and free of residual isocyanate or other monomers. While the FDA regulates polyurethane resins for food-contact applications, a specific FDA cosmetic status for POLYURETHANE-64 is not currently documented.
Your Skin
Skin Compatibility
Our Assessment
Verdict
POLYURETHANE-64 is a valuable functional ingredient that creates a protective film to support skin hydration and barrier function, demonstrating a high safety profile when properly formulated.
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