Science
Mechanism of Action
Functioning primarily as a film-forming agent, Polyurethane-63 creates a resilient, flexible network upon application. This network adheres to the skin, providing a physical barrier that can help reduce transepidermal water loss, thus supporting skin hydration and potentially aiding in its natural regenerative processes.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Polyurethane-63, a complex polymer featuring a polyester diol backbone, is susceptible to hydrolytic degradation, particularly at lower pH levels. In contrast, polyether-based polyurethanes generally exhibit greater stability at higher pH. While polyurethanes typically offer good resistance to high-pH chemicals, their specific performance is influenced by concentration and temperature. Its waterborne nature and numerous functional groups allow for versatile formulation possibilities.
Conflicts
- Residual diisocyanate monomers: The presence of unreacted diisocyanate monomers must be strictly minimized due to their association with irritation, allergic contact dermatitis, and respiratory issues.
- Sensitizers in raw material mixtures: Formulators must carefully manage the total concentration of potential sensitizers, such as methylisothiazolinone (MI), which may be present in raw material emulsions or solutions of polyurethanes.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has determined that polyurethanes, including Polyurethane-63, are safe for use in cosmetic products when formulated to be non-sensitizing. The CIR panel specifically noted the absence of residual isocyanate or other monomers in these ingredients as supplied. However, formulators should exercise caution regarding raw materials that may contain sensitizers like methylisothiazolinone (MI). While certain polyurethanes used in medical contexts have shown mild inflammatory responses in animal studies, Polyurethane-63 is considered safe for its intended cosmetic applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Polyurethane-63 is a valuable film-forming agent, providing a flexible, hydrating barrier on the skin, and is deemed safe for cosmetic use with appropriate formulation considerations.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources