Science
Mechanism of Action
As a cationic polymer, Polyquaternium-99 possesses a positive charge, enabling it to ionically bond with the negatively charged surfaces inherent to skin and hair. This interaction facilitates the formation of a superficial, protective film which can effectively mitigate transepidermal water loss and provide a barrier against external irritants. Furthermore, in alignment with other members of the polyquaternium class, it may function as a humectant, drawing and binding moisture from the ambient environment to enhance skin hydration.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The specific optimal pH range for Polyquaternium-99 is currently undefined. However, polyquaterniums as a class generally demonstrate stability across a wide pH spectrum; for instance, related compounds maintain stability within ranges such as pH 5.5-8.5.
Conflicts
- anionic surfactants
Safety
Safety Profile
Polyquaternium-99 has not been specifically assessed by the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS). While the CIR has reviewed other polyquaterniums (e.g., Polyquaternium-22, -39) deeming them safe for cosmetic use, they emphasized the need for specific residual monomer/polymerization profiles for each ingredient. Its large, highly polar molecular structure generally suggests low systemic absorption potential.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Polyquaternium-99 exhibits promising conditioning properties consistent with its class, but the current lack of specific clinical efficacy, safety, and skin compatibility data necessitates further targeted research for a definitive recommendation.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources