Science
Mechanism of Action
As a polymeric quaternary ammonium salt, Polyquaternium-65 possesses a positive charge, enabling it to electrostatically interact with negatively charged biological surfaces, such as skin and hair. This interaction facilitates the formation of a cohesive film, which contributes to conditioning properties and resistance to rinse-off. Furthermore, it stabilizes multi-phase systems by acting as an effective emulsion stabilizer, preventing separation of oil and water components.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
EWG's Skin Deep assessment indicates a 'LOW' concern across categories including Cancer, Allergies & Immunotoxicity, and Developmental and Reproductive Toxicity, and it is not featured on their Restricted or Unacceptable Lists.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While demonstrating value as an emulsion stabilizer and hair conditioning agent, there is currently insufficient direct clinical data to comprehensively assess its primary role or efficacy within precision skincare formulations.
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References
Sources