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POLYQUATERNIUM-60.

Insufficient Data CAS 351425-04-2 / ANTISTATIC, HAIR CONDITIONING

Polyquaternium-60 is a cationic polymer engineered to enhance skin hydration and provide a protective surface barrier. Its positive charge allows it to electrostatically bind to the skin, forming a conditioning film that minimizes moisture loss and shields against environmental factors.

humectant film-forming agent skin conditioning protective barrier

Science

As a cationic polymer, Polyquaternium-60 possesses inherent positive charges, enabling it to electrostatically bond with the negatively charged surface of the skin. This characteristic ensures its adherence and film-forming capability, resisting rinse-off. It functions as a humectant by attracting atmospheric moisture and binding it to the skin, thereby improving hydration levels. Concurrently, its film-forming properties establish a protective barrier on the skin's surface, effectively minimizing transepidermal water loss and defending against environmental irritants, culminating in skin that feels smoother, softer, and more conditioned.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4 – 8
0 7 14

Stability

Optimal functionality, specifically regarding charge density and overall effectiveness, is maintained within a pH range of 4 to 8. Efficacy may diminish outside this window.

Conflicts

  • strong oxidizing agents
  • iron
  • iron salts
  • steel
  • copper
  • copper alloys
  • aluminum
  • anionic surfactants (can form complexes)

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

There is no dedicated CIR (Cosmetic Ingredient Review) safety assessment available for Polyquaternium-60. However, the CIR has evaluated other polyquaterniums (e.g., Polyquaternium-6, -11, -22, -39), generally concluding their safety in cosmetic formulations at specified concentrations. Polyquaternium-6 holds FDA approval as an indirect food additive. For Polyquaternium-60, EWG indicates 'No Data' for common concerns such as skin allergies/irritation, developmental/reproductive toxicity, and respiratory issues.


Your Skin

No Normal
Yes Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While demonstrating a clear mechanistic benefit for hydration and barrier support, Polyquaternium-60 currently has insufficient specific safety and efficacy data for a comprehensive assessment in precision skincare.


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References