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POLYQUATERNIUM-55.

Valuable CAS 306769-73-3 / HAIR FIXING

Polyquaternium-55 is a precision cationic polymer engineered to significantly elevate the sensory experience of skincare. It creates a flexible, protective film on the skin, measurably improving formula spreadability and enhancing hydration by reducing transepidermal water loss.

Film-forming Hydration-boosting Sensory enhancer Spreadability enhancer Antistatic

Science

Polyquaternium-55 operates as a positively charged, hydrophilic cationic polymer. Its mechanism involves electrostatic attraction to the inherently negatively charged areas of the skin, where it forms a thin, resilient, and heat-resistant polymeric film. This film demonstrably enhances the cosmetic elegance of formulations by improving slip and glide, while simultaneously functioning as a vital barrier to mitigate transepidermal water loss (TEWL), thereby promoting sustained skin hydration and a perceptibly smooth skin finish.


Research

Medium confidence
Effective range 0.1–2%
Optimal

N/A

Key findings

  1. 01 Demonstrated efficacy in concentrations of 0.5% to 2% for enhancing sensory experience, resulting in a silky and smooth skin feel. It improves product spreadability and glide, and has been shown to form a protective barrier on the skin, reducing transepidermal water loss and promoting hydration. A general recommended usage rate in final formulations for skincare products is between 0.1% and 0.5%.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 3.5 – 7
0 7 14

Stability

Optimal stability and efficacy are observed within a pH range of 3.5 to 7.0. Formulations outside this specified range may experience degradation or a reduction in the ingredient's essential charge density, potentially compromising its performance.

Conflicts

  • Strong sulfates may reduce the ingredient's deposition efficiency, potentially diminishing its intended benefits.

Safety

CIR Status
Not reviewed
Sensitization risk Low

While generally regarded as a low-risk and non-irritating cosmetic ingredient, a specific Cosmetic Ingredient Review (CIR) safety assessment providing a definitive 'safe as used' conclusion or a maximum concentration limit has not been identified.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Medium
Comedogenicity Medium

Our Assessment

Valuable

Polyquaternium-55 is a valuable ingredient for enhancing the sensory experience and hydration in skincare formulations, forming a protective film on the skin.


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