Science
Mechanism of Action
The primary mechanism of action for Polyquaternium-110 is observed exclusively on hair. It functions by depositing via coacervate formation, initially creating lamellar structures that facilitate wet combing and provide a lubricating effect. As hair dries, these lamellar structures undergo a transformation into hexagonal formations, which are responsible for imparting a noticeable volume boost. No specific mechanism of action on the skin has been elucidated.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Concentrations between 1-3% are utilized for hair volumization, with 2% generally recommended for Caucasian hair and 3% for Asian hair types.
- 02 A 2% concentration incorporated into a European market volume shampoo demonstrated a 40% improvement in volume performance after a 24-hour period.
- 03 When co-formulated in a shampoo base with 0.25% Polyquaternium-7, a notable increase in volume performance was observed: 213% after one hour and 48% after 24 hours.
- 04 Instrumental evaluations on Caucasian grey hair revealed that formulations containing Polyquaternium-110 led to a 29% increase in volume sustained over 24 hours, alongside more than double the improvement in wet combing compared to an untreated base.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This polymer exhibits compatibility across a broad range of ingredient types, including cationic, anionic, and non-ionic compounds, allowing for seamless integration with existing traditional conditioning polymers.
Synergies
- Traditional conditioning polymers (e.g., Polyquaternium-7 for enhanced volume performance)
Safety
Safety Profile
Polyquaternium-110 currently lacks dedicated safety assessments from major regulatory bodies such as CIR, SCCS, or FDA. While safety data exists for related Polyquaternium compounds, these findings are not directly applicable to Polyquaternium-110.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Polyquaternium-110 demonstrates strong evidence of efficacy for hair volumization and enhanced wet combing; however, its potential utility and safety specifically for skin applications remain largely unassessed.
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References
Sources