Science
Mechanism of Action
This ingredient operates as a cationic conditioning agent, leveraging its positive charge to adsorb onto the proteinaceous surfaces of the skin. It attracts ambient moisture, establishing a thin, continuous film that both hydrates and creates a protective barrier against transepidermal water loss. Furthermore, it exhibits surfactant properties, aiding in the removal of impurities, and crucially, can mitigate potential irritation from other cleansing agents.
Research
Clinical Evidence
High confidence0.2%
Key findings
- 01 Significantly boosts product viscosity and slip, imparting a rich, elegant feel to skincare formulations.
- 02 Increases skin hydration and establishes a protective layer that effectively retains moisture in skincare products.
- 03 Demonstrated low irritation/sensitization potential in human testing and can mitigate irritation caused by anionic surfactants when used in cleansers.
Transparency
Dusting Analysis
While generally well-tolerated at typical cosmetic concentrations, POLYQUATERNIUM-10 has been shown to cause mild skin and eye irritation at concentrations reaching 5%. This indicates a clear concentration-dependent safety profile, not an issue of insufficient dosage for efficacy.
The Formula
Formulation
Stability
POLYQUATERNIUM-10 maintains stability across a broad pH range of 4 to 8, with optimal performance typically observed between pH 4 and 6. Elevated pH levels may, however, reduce its high water solubility due to the presence of hydroxyl groups.
Synergies
- Non-ionic surfactants
- Amphoteric surfactants
Conflicts
- Anionic surfactants (specifically at concentrations above 1%, which can lead to flocculation)
Safety
Safety Profile
Extensively evaluated by the CIR, POLYQUATERNIUM-10 is deemed safe for cosmetic applications at current usage levels. It is considered entirely safe and non-irritating at concentrations up to 2%, with human testing confirming low irritation and sensitization potential. However, it is important to note that concentrations of 5% are associated with mild irritation to skin and eyes.
Your Skin
Skin Compatibility
Our Assessment
Verdict
POLYQUATERNIUM-10 is a valuable conditioning polymer that significantly enhances skin hydration, feel, and product formulation, with a strong safety profile at effective concentrations.
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References
Sources