Science
Mechanism of Action
This ingredient primarily acts as a skin conditioning agent, contributing to the maintenance of healthy skin. As a derivative of polyethylene glycol (PEG), it offers emollient benefits, stabilizes emulsions, and can facilitate the penetration of other active compounds. Additionally, it forms a thin film on the skin's surface, which helps to retain moisture and impart hydrophobic and oleophobic properties.
Research
Clinical Evidence
Low confidence0.5%-5.0% for water repellency
Key findings
- 01 A study demonstrated that this ingredient exhibits water/oil repellency, with an effective concentration range between 0.5% and 5.0%. Concentrations below 0.5% yielded inconclusive water repellency, while concentrations exceeding 5.0% potentially reduced this effect.
Transparency
Dusting Analysis
Respiratory concerns have been noted for this ingredient, particularly when present in inhalable forms such as sprays or powders. This potential risk is a contributing factor to its classification as unacceptable for EWG VERIFIED products.
The Formula
Formulation
Stability
Unneutralized solutions of PFPE phosphate typically present a low pH, ranging from 2.0 to 3.0. Hydroalcoholic solutions containing this ingredient achieve peak water repellency performance when maintained at a pH below 3.5.
Conflicts
- Potential contamination with Ethylene Oxide and 1,4-Dioxane (as identified by EWG for the ingredient class).
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that data were insufficient to establish the safety of 'fluorinated polyethers,' a category encompassing this ingredient. Identified as a Per- and Polyfluoroalkyl Substance (PFAS), it is deemed 'unacceptable for use in EWG VERIFIED products' due to potential respiratory concerns from inhalation (e.g., in sprays or powders) and risks of contamination with Ethylene Oxide and 1,4-Dioxane. Furthermore, certain PFAS are banned or deemed unsafe in cosmetics by California. Conversely, the FDA has determined 'Polyperfluoroethoxymethoxy PEG-2 Phosphate' to be safe for general or specific, limited applications in food.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite its conditioning and repellency benefits, the ingredient's classification as a PFAS, insufficient safety data from CIR, and potential for respiratory concerns warrant its avoidance in precision skincare formulations.
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