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POLYGLYCERYL-10 PENTACAPRYLATE.

Valuable CAS - / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

Polyglyceryl-10 Pentacaprylate is a non-ionic polyglyceryl fatty acid ester, recognized for its multifunctional properties in skincare formulations. It primarily acts as a versatile surfactant, emulsifier, and solubilizer, enabling the stable integration of diverse ingredients while enhancing overall product texture and cleansing efficacy.

Summary

Emulsifying Surfactant/Cleansing Solubilizing Solvent Emollient Light Stabilizer

Science

Mechanism of Action

Functioning as a non-ionic surfactant and emulsifier, Polyglyceryl-10 Pentacaprylate effectively stabilizes oil-in-water formulations, contributing to an optimized product texture. It facilitates the solubilization of lipophilic substances, such as fragrances and essential oils, into aqueous systems, and serves as a mild cleansing agent and solvent on the skin.

Research

Clinical Evidence

Medium confidence
Effective range 2.5–10%
Optimal

N/A

Key findings

  1. 01 Related polyglyceryl-10 caprylates demonstrated effective makeup removal efficacy by self-assembling into transparent nanoparticles in water, observed at concentrations between 2.5 wt% and 10 wt%.
  2. 02 A related polyglyceryl-10 caprylate exhibited moderate irritation potential, with a HET-CAM score of 8.4 at 4 wt%, which is notably lower than PEG-6 caprylic/capric glycerides (severe irritant, score of 14.1).

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 8
0 7 14

Stability

This non-ionic ingredient demonstrates stability within a pH range of 4.0 to 8.0, ensuring broad compatibility across various formulations. It can be incorporated into the oil phase and tolerates heat, though sustained temperatures exceeding 80°C should be avoided to maintain optimal stability.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
10%
Sensitization risk Low

The CIR Expert Panel concluded that Polyglyceryl-10 Caprylate, and a family of 274 related polyglyceryl fatty acid esters, are safe for use in cosmetics when formulated to be non-irritating and within typical concentrations (e.g., up to 10%). It is also approved for food use and is considered a desirable alternative to PEG-based ingredients, helping to mitigate the potential risk of 1,4-dioxane by-product formation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Polyglyceryl-10 Pentacaprylate is a valuable non-ionic surfactant and emulsifier, offering excellent formulation stability, gentle cleansing, and broad skin compatibility, making it suitable for a wide range of cosmetic products.

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