Science
Mechanism of Action
As an amphiphilic molecule, Poloxamine 1304 effectively reduces the interfacial tension between disparate liquid phases, such as oils and water. This critical function enables the formation and stabilization of homogenous emulsions, preventing phase separation and ensuring uniform ingredient distribution within cosmetic products.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Poloxamine 1304 exhibits high versatility, being soluble in both water and a wide array of organic solvents. It maintains stability across a broad pH range, making it highly adaptable for diverse product chemistries. Optimal stability is maintained when stored under recommended conditions, shielded from extreme temperatures and direct sunlight.
Safety
Safety Profile
While Poloxamine 1304 specifically lacks an individual Cosmetic Ingredient Review (CIR) assessment, broader safety evaluations for the Poloxamer family indicate their safety in cosmetic applications. It is not classified as a hazardous substance. Specific dermal toxicity for Poloxamine 1304 is currently undetermined, and neither the SCCS nor FDA has issued a dedicated safety opinion for this particular compound, though an SCCNFP opinion addressed its nomenclature.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Poloxamine 1304 is a valuable formulation excipient, critical for achieving product homogeneity and stability across a wide range of cosmetic and personal care applications.
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References
Sources