Science
Mechanism of Action
This synthetic block copolymer, a specific type within the poloxamine family, is constructed from ethylene oxide and propylene oxide components surrounding an ethylenediamine core. Its distinct amphiphilic nature, which includes both water-attracting (hydrophilic) and oil-attracting (lipophilic) segments, enables it to effectively decrease interfacial tension between immiscible liquids like oil and water. This fundamental action is key to forming and maintaining stable, uniform emulsions in various product matrices.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Poloxamines, including Poloxamine 1102, may demonstrate sensitivity to variations in temperature and pH due to their central amine groups, which could influence their functional properties. However, a closely related counterpart, Poloxamine 1307, is documented to exhibit stability across a broad pH range. Generally, maintaining stability requires storage under recommended conditions, away from extreme temperatures and direct solar exposure.
Safety
Safety Profile
While Poloxamine 1102 is acknowledged by the SCCS as an emulsifier, a dedicated safety assessment detailing its status or specific maximum concentration by either the CIR or SCCS has not been identified. Broader data on poloxamers generally indicate low toxicity and limited skin penetration. There is currently no specific FDA approval status for Poloxamine 1102 as a cosmetic ingredient.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Poloxamine 1102 is a recognized emulsifier and stabilizer, essential for product formulation, but comprehensive safety and skin compatibility data from authoritative regulatory bodies remain insufficient, necessitating careful consideration in development.
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References
Sources