Science
Mechanism of Action
As an emulsifier, Poloxamine 1101 forms stable dispersions of immiscible liquids, ensuring consistent product texture and efficacy. Its surfactant properties reduce surface tension, allowing water to mix more readily with oils and debris on the skin's surface, enabling their efficient rinse-off. The presence of tertiary amine central groups contributes to its inherent thermodynamic stability and pH-sensitive behavior within formulations.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Poloxamine 1101 enhances formulation stability through its role as a stabilizer, leveraging its thermodynamic properties and pH sensitivity. It can also be effectively incorporated into hydrogel systems.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not published a specific safety assessment for Poloxamine 1101. While The Good Scents Company reports 'Not determined' for toxicity and 'None found' for GHS classification, Chemsrc lists 'Xi: Irritant' hazard codes and 'Risk Phrases 36/37/38' (irritating to eyes, respiratory system, and skin) for the raw chemical. However, poloxamines as a class are generally approved by the FDA for various uses, including drug carriers and food additives.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Poloxamine 1101 is a valuable functional ingredient for formulating stable cosmetic products, though more specific safety and skin-benefit data for this individual compound would be beneficial.
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References
Sources