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Moumoujus

PISCUM LECUR OIL.

Valuable CAS 8009-00-5 / SKIN CONDITIONING - EMOLLIENT

Piscum Lecur Oil, commonly known as Cod Liver Oil, is a rich source of omega-3 fatty acids valued for its moisturizing and reparative properties. It enhances skin barrier function, calms inflammation, and supports overall skin health, making it particularly beneficial for dry and compromised skin conditions.

Summary

Emollient Moisturizer Skin Protectant Anti-inflammatory Antimicrobial Antiviral Wound Healing

Science

Mechanism of Action

Piscum Lecur Oil primarily moisturizes by increasing the skin's water content and supports general skin health. Its key components, notably omega-3 polyunsaturated fatty acids (PUFAs) like DHA and EPA, enhance the skin barrier, mitigate UV-induced inflammation and hyperpigmentation, alleviate dry skin and itching associated with dermatitis, and accelerate wound healing. These PUFAs exert anti-inflammatory effects by competing with arachidonic acid to inhibit pro-inflammatory eicosanoid production and by regulating cytokines essential for wound repair. Furthermore, oxygenated metabolites such as resolvins and protectins derived from EPA and DHA possess potent anti-inflammatory and immunoregulatory actions that facilitate inflammation resolution. The oil's fatty acids also exhibit antibacterial activity, primarily by disrupting cellular membranes, and can act as penetration enhancers for other active ingredients.

Research

Clinical Evidence

High confidence
Effective range 1–20%
Optimal

5-13.56%

Key findings

  1. 01 Demonstrates moisturizing effects by increasing skin water content and exhibits general skin-caring properties.
  2. 02 A fatty acid extract from cod liver oil showed significant antibacterial activity against various Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pyogenes.
  3. 03 A fatty acid extract from cod liver oil achieved a 50,000-fold (≥4.7 log10) reduction in herpes simplex virus type 1 (HSV-1) activity within 10 minutes.
  4. 04 Used in topical formulations for the treatment of wounds and various skin disorders.
  5. 05 Approved by the FDA for use in Over-the-Counter (OTC) skin protectant products.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 4.2 – 5.6
0 7 14

Stability

Crude Piscum Lecur Oil requires refining to remove free fatty acids, pigments, and contaminants that can cause off-flavors or odors. Its fatty acid extracts can contribute to acidic pH values in formulations. Maintaining a product pH between 4.2 and 5.6, consistent with the skin's natural surface pH, is crucial to prevent potential irritation or redness. Emulsifiers are typically necessary to integrate this oil into water-based systems.

Synergies

  • Acts as a penetration enhancer for other active substances in topical formulations.

Safety

Safety Profile

CIR Status
Deferred evaluation
Max tested
13.56%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deferred evaluation, citing that its safety has been assessed by the FDA. The FDA permits its use in OTC skin protectant products at concentrations between 5% and 13.56%. Furthermore, Piscum Lecur Oil adhering to European animal by-product regulations is permissible in cosmetics marketed within the EU under the Cosmetics Regulation.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Piscum Lecur Oil is a valuable multi-functional ingredient, offering significant moisturizing, skin-protective, anti-inflammatory, and antimicrobial benefits, particularly for dry and compromised skin, with a well-established safety profile for topical use.

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