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Moumoujus

PISCUM CARTILAGE EXTRACT.

Insufficient Data / SKIN CONDITIONING

Piscum Cartilage Extract, derived from various fish sources, is a rich complex of collagen and proteoglycans. This ingredient is designed to enhance skin hydration, improve texture, and bolster elasticity, offering notable anti-aging benefits.

Summary

Skin Conditioning Anti-aging (Wrinkle Reduction) Elasticity Improvement Hydration Enhancement Skin Texture Improvement Complexion Enhancement Oil Production Control Soothing Anti-inflammatory Skin Barrier Support Collagen Morphology Improvement Dermal Density Enhancement

Science

Mechanism of Action

This extract functions by reinforcing the skin's extracellular matrix, primarily via its collagen and proteoglycan content. Proteoglycans are integral for maintaining skin's structural integrity and hydration, contributing to improved elasticity. When hydrolyzed, fish cartilage has been shown to increase dermal density, refine collagen morphology, and reduce elastosis, thereby diminishing the appearance of wrinkles and improving overall skin texture. It also provides anti-inflammatory and soothing effects, supports skin barrier function, and may help mitigate signs of premature aging and acne.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

0.125-5% (topical)

Key findings

  1. 01 Topical application of 0.125-5% lyophilized hydrolyzed shark cartilage gel significantly improved skin moisture, texture, and complexion, while controlling oil and providing a wrinkle-smoothing effect on human inner wrist skin within 10-20 minutes.
  2. 02 Daily oral intake of 20 mg proteoglycans derived from salmon nasal cartilage significantly improved skin elasticity, hydration, and reduced roughness, wrinkles, and pigmentation over 56 days in healthy adults.
  3. 03 Low-dose oral supplementation with hydrolyzed fish cartilage (Cartidyss® NG) reduced wrinkles, increased dermis echogenicity (suggesting improved dermal density), and improved collagen morphology and reduced elastosis over a 90-day period in healthy females.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 2 – 5
0 7 14

Stability

Fish collagens, which are key components of cartilage extract, exhibit high solubility in acidic pH ranges, typically between pH 2 and 5. To prevent degradation of sensitive components like chondroitin sulfate, high temperatures and alkaline conditions must be avoided during both extraction and formulation. Elevated moisture content and heat can accelerate unwanted reactions, impacting overall stability.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Comprehensive safety references, GHS classifications, and dermal toxicity data for Piscum Cartilage Extract are not readily available. It has not been formally reviewed by the Cosmetic Ingredient Review (CIR) Expert Panel, leaving its cosmetic safety profile largely unassessed.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Piscum Cartilage Extract demonstrates promising efficacy in improving multiple skin parameters, the absence of comprehensive safety data and a CIR review necessitates further rigorous investigation for its use in precision skincare.

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