Science
Mechanism of Action
This pigment functions by depositing its synthetic diketopyrrolopyrrole (DPP) structure onto target surfaces, absorbing specific wavelengths of light and reflecting red, thereby imparting its characteristic color. Its molecular design contributes to excellent stability against UV light exposure and chemical degradation, ensuring long-lasting color retention.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 A 10% concentration of Pigment Red 57:1, when diluted in propylene glycol and applied to rabbit skin, demonstrated no observable irritation. Similarly, a 10% aqueous solution showed no staining of orbital tissues in animal eye irritation tests, indicating a favorable safety profile regarding acute dermal and ocular exposure.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Pigment Red 57:1 presents as a bluish-red powder. While generally insoluble in cold water (8.9mg/L at 25°C), it can dissolve in hot water, yielding a yellowish-red color. It maintains stability at 0.5% in water for 7 days at room temperature and exhibits 95% recovery after 7 months in cosmetic formulations at 25°C, though further data was requested for specific applications. It demonstrates excellent chemical stability and heat resistance up to 220-240°C, especially at concentrations above 0.1%.
Conflicts
- Alkaline environments (can cause thickening due to metal ion substitution)
Safety
Safety Profile
The Scientific Committee on Consumer Safety (SCCS) of the EU Commission has evaluated Pigment Red 57, allowing its use as a coloring agent in all cosmetic products under Annex IV, part 1 of Directive 76/768/EEC. A maximum concentration of 0.4% is permitted for its specific use as a direct dye in non-oxidative semi-permanent hair dye formulations. While an SCCS opinion in 2012 indicated a need for further percutaneous absorption data for this specific hair dye application, it is generally considered safe for cosmetic use within established restrictions. It is also legally permitted as Food Red No. 7. The EWG Skin Deep database reports low concerns for cancer, allergies & immunotoxicity, and developmental & reproductive toxicity, but also notes high 'Use restrictions' and 'Contamination concerns'.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Pigment Red 57:1 is a valuable cosmetic colorant, providing a stable red hue with low irritancy and comedogenicity, though formulators should note its alkaline incompatibility and the specific 0.4% maximum for hair dye applications.
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