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Moumoujus

PICRASMA QUASSIOIDES WOOD EXTRACT.

Insufficient Data / SKIN PROTECTING

Picrasma Quassioides Wood Extract is a multi-functional botanical ingredient recognized for its comprehensive benefits, including robust antioxidant and anti-inflammatory properties. It provides protective, soothing, and anti-melanogenic effects to promote healthier, more resilient skin.

Summary

skin protecting antioxidant soothing anti-inflammatory antibacterial anti-melanogenic anti-apoptotic astringent

Science

Mechanism of Action

This extract actively neutralizes damaging free radicals, significantly suppressing superoxide radicals by up to 50.50% and hydroxyl radicals by up to 30%. It mitigates inflammatory responses by decreasing inflammatory cytokine iNOS mRNA levels and inhibiting factors like MMP1. Additionally, it supports cell survival under UVB exposure, downregulating apoptotic markers such as caspases, p53, and Bax, while also exhibiting anti-melanogenic, antibacterial, and astringent properties.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies utilizing 100 μg/mL concentrations of methanol and ethanol extracts demonstrated potent antioxidant activity, suppressing superoxide radicals by 50.50% and 47.90% respectively, and hydroxyl radicals by 20% and 30% respectively.
  2. 02 Further in vitro research revealed that an ethanol extract (Pq-EE), at undisclosed concentrations, inhibited free radicals in a dose-dependent manner. It also promoted cell survival under UVB exposure, downregulated mRNA levels of apoptotic factors, decreased MMP1 and inflammatory cytokine iNOS mRNA levels, and inhibited caspases, cleaved caspases, p53, and Bax.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Specific safety assessments for topical cosmetic use by regulatory bodies like CIR, SCCS, or FDA are currently unavailable. While studies on internal use or high in-vitro concentrations of specific plant compounds have indicated potential toxicity (e.g., hypotension, nausea, cytotoxicity), these findings are not directly applicable to the safety of the topical wood extract at typical cosmetic concentrations.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While exhibiting promising multi-functional benefits in vitro, a lack of human clinical trials and specified topical concentration data necessitates further research to definitively assess its efficacy and safety in precision skincare applications.

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