Science
Mechanism of Action
Operating at a cellular level, PICHIA/SEA SALT FERMENT LYSATE EXTRACT supports skin regeneration by stimulating cellular turnover, which refines texture and overall appearance. It enhances the skin's natural barrier function, thereby improving moisture retention and preventing dryness, thus acting as a potent moisturizer and humectant. Furthermore, it defends against oxidative stress and free radical damage with its antioxidant properties. The extract also exhibits soothing actions, reducing irritation and redness, and contributes to anti-aging effects by potentially restoring the dermal-epidermal junction (DEJ) and mitigating inflammation. Specific components from Pichia pastoris fermentation have been noted to resist allergies, relieve discomfort, reduce inflammation, prevent sunburn, regulate skin's micro-ecology, control oil production, and facilitate skin barrier repair.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While the optimal pH for Pichia pastoris fermentation itself is identified as 6.0 (with growth possible from 3.0 to 7.0), specific optimal pH ranges for the stability of the final extract in a cosmetic formulation are currently not available. Product stability may depend on various factors including the overall formulation pH and other ingredients.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has found insufficient data for certain yeast-derived ingredients, including 'Pichia Ferment Lysate Filtrate', under intended conditions of use. Although 'Pichia Ferment Lysate Filtrate' is listed as 'SAFE INGREDIENT' by some sources without specific regulatory citations, the GHS classification for 'Pichia/sea silt ferment lysate extract' indicates 'None found' for hazards and dermal toxicity is 'Not determined'. This suggests a lack of known hazards, but also highlights the absence of comprehensive, publicly available safety testing data specific to this ingredient for a definitive assessment by regulatory bodies like CIR.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This ferment lysate extract shows promising multi-functional benefits for skin regeneration, hydration, and defense based on a clinical patent; however, comprehensive safety data, particularly from regulatory bodies like CIR, is currently insufficient for a definitive assessment.
Related
Similar Ingredients
Finding similar ingredients…