Science
Mechanism of Action
The compound exerts its beneficial effects through the synergistic action of its three key constituents. *Pichia Pastoris* ferment filtrate acts as a skin conditioning and protecting agent, providing emollient properties and potentially upregulating cellular activity. Diethylhexyl Syringylidenemalonate serves as a potent broad-spectrum antioxidant, adept at quenching singlet oxygen and scavenging reactive oxygen species, while crucially stabilizing UV filters (particularly avobenzone), boosting SPF, and improving UVA protection. Tocopherol, commonly known as Vitamin E, further augments this antioxidant defense. Collectively, these components contribute to enhanced skin resilience, protection against oxidative damage, and optimized photoprotection.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient exhibits optimal stability within an acidic to neutral pH range, specifically between 5.0 and 7.0. This is due to the susceptibility of Diethylhexyl Syringylidenemalonate and Tocopherol to hydrolysis under strong alkaline conditions. Furthermore, formulations containing this ingredient should be protected from light to preserve the integrity and efficacy of Tocopherol.
Conflicts
- strong alkaline conditions
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has determined that 'Pichia Ferment Extract Filtrate' and 'Pichia Pastoris Ferment Filtrate' currently have insufficient data for a safety determination, specifically requesting dermal sensitization and toxicity data. In contrast, Diethylhexyl Syringylidenemalonate is generally considered safe, not meeting GHS hazard criteria and showing no significant cytotoxicity in in vitro studies at cosmetic concentrations. Tocopherol is also broadly recognized as safe for topical use. The overall safety assessment for this blend is pending further information on the *Pichia* ferment component.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While offering promising antioxidant, UV stabilizing, and skin-conditioning benefits suitable for all skin types, the current lack of comprehensive safety data for the *Pichia Pastoris* ferment component necessitates careful consideration.
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