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Moumoujus

PICHIA/OSAJIN FERMENT EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Pichia/Osajin Ferment Extract is a powerful bio-ferment derived from Pichia pastoris, engineered to comprehensively enhance skin health. It targets moisture retention and barrier integrity while simultaneously offering anti-inflammatory, antioxidant, and oil-balancing benefits.

Summary

Moisture Retention Skin Barrier Reinforcement Cell Turnover Stimulation Skin Regeneration Texture Improvement Antioxidant Protection Anti-inflammatory Redness Reduction Dermal-Epidermal Junction Restoration Oil Control Micro-ecology Regulation Allergy Resistance

Science

Mechanism of Action

This ingredient works by bolstering skin hydration and strengthening its natural protective barrier. It actively supports cellular turnover and regeneration, leading to an improved epidermal texture and appearance. Pichia/Osajin Ferment Extract provides antioxidant defense against free radical damage, calms irritation and redness, restores the dermal-epidermal junction, and helps regulate sebaceous activity by reducing cellular lipid secretion.

Research

Clinical Evidence

Medium confidence
Effective range 1–10%
Optimal

5%

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH 5 – 6
0 7 14

Stability

Optimal pH for Pichia pastoris fermentation typically ranges from 5.0 to 6.0. It's noted that fermentation media may experience precipitation above pH 4.5, suggesting potential pH sensitivity during formulation.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
2%
Sensitization risk Low

The CIR Expert Panel has determined that Pichia Ferment Extract Filtrate and Lysate Filtrate, derived from Pichia pastoris, are safe for cosmetic application at current usage concentrations and practices, provided they originate from yeast species with established dermal sensitization and food use safety. The highest reported concentration in cosmetic products is 2%. While an oral study in mice indicated reproductive effects, these were at significantly elevated doses and are not considered relevant to typical cosmetic exposure.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Pichia/Osajin Ferment Extract is a valuable, multifaceted ingredient that effectively improves skin hydration, fortifies the barrier, and provides significant anti-inflammatory and oil-regulating benefits across all skin types.

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