Science
Mechanism of Action
This ingredient functions by directly scavenging harmful reactive oxygen species like superoxide anion and hydroxyl radicals. It also supports the skin's natural defense system by restoring cellular glutathione levels and enhancing the activity of critical enzymes such as superoxide dismutase and catalase, particularly after UVB exposure. Furthermore, Phloroglucinol stimulates keratinocyte proliferation, which is essential for promoting skin regeneration and mitigating signs of chronological and light-induced aging.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability is achieved at pH below 5.5. It is known to be unstable in neutral-to-alkaline formulations. Discoloration may occur due to light exposure and air oxidation, potentially resulting in a beige tint. Storage in a dry place, protected from direct light and UV radiation, is crucial for maintaining stability.
Conflicts
- Unstable in neutral-to-alkaline formulations (pH above 5.5).
- Susceptible to discoloration from light and air oxidation.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Panel has deemed available data insufficient to conclude Phloroglucinol's safety in cosmetic products, necessitating further evaluation. This ingredient is known to infrequently induce cutaneous hypersensitivity reactions, is classified as a cause of skin irritation, serious eye irritation, and potential allergic skin reactions. Additionally, there is suspicion it may cause genetic defects.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite promising antioxidant and regenerative properties, Phloroglucinol is not recommended for cosmetic use due to insufficient safety data from the CIR, documented risks of irritation, allergic reactions, and suspected genotoxicity.
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