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PHEOPHORBIDE A AMIDO PEG-45 AMIDO DISTEAROYL GLYCEROPHOSPHOETHANE.

Insufficient Data / ANTI-SEBUM, ANTIMICROBIAL, ANTIOXIDANT

This complex integrates Pheophorbide a, a chlorophyll breakdown product known for its photosensitizing capabilities, with PEG-45 and a distearoyl glycerophosphoethane lipid moiety. This engineered structure is designed to enhance the solubility and stability of Pheophorbide a, potentially making it more suitable for diverse formulations.

Photosensitizer Humectant Solvent Binding Agent

Science

The primary active component, Pheophorbide a, functions as a photosensitizer, capable of reacting with oxygen to produce reactive oxygen species (ROS) when exposed to light. The Polyethylene Glycol (PEG-45) segment contributes to the molecule's properties as a binding agent, humectant, and solvent, significantly improving its water solubility and overall stability. The distearoyl glycerophosphoethane component likely confers lipid solubility, allowing for amphiphilic characteristics within formulations.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

While raw Pheophorbide a exhibits poor aqueous solubility and limited stability in water (not recommended for storage beyond one day), its PEGylation significantly enhances water solubility. The inclusion of distearoyl glycerophosphoethane also suggests improved solubility in lipid environments, rendering the complex amphiphilic.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments (CIR, SCCS, FDA) are available for the full complex 'PHEOPHORBIDE A AMIDO PEG-45 AMIDO DISTEAROYL GLYCEROPHOSPHOETHANE'. Raw Pheophorbide a is generally considered hazardous, necessitating review of its Safety Data Sheet. PEGs are broadly considered safe in cosmetic and pharmaceutical applications, with PEGylation often reducing immunogenicity and enhancing molecular stability. However, the lack of data for the specific complex warrants caution.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

This ingredient, while engineered for enhanced solubility and stability, lacks specific safety and efficacy data for cosmetic use, and its core component's photosensitizing nature requires careful consideration.


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