Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

PHENYLACETONITRILE.

Avoid CAS 140-29-4 / FRAGRANCE

Phenylacetonitrile is a chemical compound primarily employed as a fragrance ingredient in cosmetic formulations and as an intermediate in flavor and perfume synthesis. However, its application in skincare is severely limited due to its high toxicity and significant potential for skin irritation.

Summary

Fragrance Antifungal

Science

Mechanism of Action

Unknown.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Phenylacetonitrile exhibits stability under typical temperatures and pressures but is susceptible to degradation in the presence of moisture.

Conflicts

  • Strong acids
  • Strong bases
  • Strong oxidizing agents
  • Strong reducing agents
  • Sodium hypochlorite

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.0001%
Sensitization risk High

This ingredient is classified as toxic if ingested, absorbed dermally, or inhaled, posing significant health risks. Direct contact can lead to irritation of the skin, eyes, and mucous membranes. Its use in cosmetics, particularly as a naturally derived fragrance, is stringently regulated by IFRA, restricting concentrations to a maximum of 0.01% (100 ppm). The FDA's overarching mandate for cosmetic product safety means that, despite not being on a specific prohibited list, its inherent toxicity and irritancy necessitate extreme caution and limitation in formulation.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to its high toxicity, significant irritancy potential, and stringent regulatory concentration limits, Phenylacetonitrile is not recommended for use in precision skincare formulations.

Related

Similar Ingredients

Finding similar ingredients…