Science
Mechanism of Action
On the skin, Phenethyl Anthranilate functions exclusively as a fragrant component, enhancing the sensory experience of a product. There is no research indicating any direct biological mechanism or beneficial action on skin beyond its aromatic properties.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
Phenethyl Anthranilate is a functional fragrance ingredient, not typically used as an inactive filler at high concentrations. Its inclusion is for its distinct aroma.
The Formula
Formulation
Stability
This ingredient is susceptible to hydrolysis under alkaline pH conditions, which may impact its stability and efficacy in certain formulations.
Conflicts
- Alkaline pH conditions
Safety
Safety Profile
A RIFM safety assessment concluded that Phenethyl Anthranilate is not expected to be genotoxic, phototoxic/photoallergenic, and skin sensitization exposure is below the Decision-Tree for sensitization. It provides a Margin of Exposure (MOE) >100 for repeated dose and developmental toxicity. The FDA recognizes it as Generally Recognized As Safe (GRAS) for use as a flavoring agent. While human experience showed no irritation or sensitization at a 10% solution, it is classified as an irritant (Xi N) and is known to cause skin and serious eye irritation (R 36/38, H315, H319). No specific SCCS opinion for Phenethyl Anthranilate was found.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Primarily serving as a perfuming agent, Phenethyl Anthranilate's classification as an irritant, despite a low sensitization risk from RIFM, warrants careful consideration for use in precision skincare formulations, especially for sensitive skin types.
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