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Moumoujus

PG-HYDROXYETHYLCELLULOSE COCODIMONIUM CHLORIDE.

Questionable CAS 130353-64-9 / ANTISTATIC, HAIR CONDITIONING

PG-Hydroxyethylcellulose Cocodimonium Chloride is a quaternary ammonium salt primarily employed in cosmetic formulations for its notable antistatic and hair conditioning properties. It effectively neutralizes static charges on hair strands, leading to improved manageability, increased softness, and enhanced shine.

Summary

Antistatic Hair Conditioning

Science

Mechanism of Action

This ingredient functions by depositing a positive charge onto the typically negatively charged surface of hair, thereby neutralizing static electricity. This interaction also helps to smooth the hair cuticle, forming a protective film that facilitates easier combing and imparts a softer, shinier appearance. While the Hydroxyethylcellulose (HEC) component is generally recognized as non-penetrating due to its high molecular weight, specific mechanisms for direct skin benefits are not detailed in current research.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 11
0 7 14

Stability

The Hydroxyethylcellulose (HEC) portion of this ingredient exhibits robust stability across a wide pH range from 3.0 to 11.0. While stable in acidic conditions (pH 3 to 6), prolonged exposure to highly acidic environments below pH 3 may induce hydrolysis. Optimal stability is observed under neutral (pH 6 to 8) and alkaline conditions (up to pH 11). Temperature and ionic strength are additional critical factors influencing overall stability.

Conflicts

  • Surfactants
  • Pigments
  • Stabilizers

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

EWG indicates moderate concerns for asthma/respiratory issues and 'some' concerns regarding skin allergies and irritation. As a quaternary ammonium salt, it belongs to a class where some compounds (e.g., Benzalkonium Chloride) have been linked to reproductive toxicity in animals, altered neurodevelopment in cells, and impacts on cholesterol biosynthesis. EWG also highlights low concerns for neurotoxicity and endocrine disruption, alongside low-moderate concerns for non-reproductive organ system toxicity. Conversely, the Hydroxyethylcellulose (HEC) component is widely considered safe, non-irritating, hypoallergenic, and non-comedogenic, with its high molecular weight preventing skin penetration.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While demonstrating efficacy as a hair conditioning and antistatic agent, this ingredient presents potential safety concerns and lacks documented benefits for direct skin applications, rendering its inclusion in precision skincare formulations questionable.

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