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PERFLUOROOCTYLETHYL TRIETHOXYSILANE.

Avoid CAS 101947-16-4 / ANTICAKING

Perfluorooctylethyl Triethoxysilane is a surface modifying agent engineered to impart durable hydrophobic (water-repellent) and lipophobic (oil-repellent) properties to various substrates. It also functions as an anticaking, skin-conditioning, and binding agent in cosmetic formulations.

Anticaking Binding Skin conditioning Surface modifying (hydrophobic/lipophobic)

Science

This ingredient modifies surfaces by hydrolyzing its triethoxysilane groups into reactive silanol groups when moisture is present. These silanol groups subsequently form stable covalent bonds with hydroxyl groups on the substrate surface. The attached perfluorooctyl chain then confers robust water-repellent and oil-repellent characteristics. Additionally, it helps prevent powdered products from caking and can condition the skin.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The substance is considered moisture sensitive and reacts slowly with water.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

PERFLUOROOCTYLETHYL TRIETHOXYSILANE is classified as a per- and polyfluoroalkyl substance (PFAS), a chemical group known for its high environmental persistence. It has been linked to immunotoxicity, as well as reproductive and developmental toxicity in both humans and animals. Consequently, its use in cosmetics is no longer authorized in Europe, where it is identified as a persistent organic pollutant (POP) or as very persistent, very bioaccumulative, and toxic (PBT/vPvB), leading to its prohibition under the Stockholm Convention on POPs or restriction by REACH regulation. The U.S. FDA, in its 2025 report on PFAS in cosmetics, identified a similar PFAS (perfluorohexylethyl triethoxysilane) as a potential safety concern at its highest reported use levels in body lotion.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Avoid

Due to its classification as a persistent and toxic PFAS, and its prohibition in European cosmetics, this ingredient poses significant environmental and health risks and should be avoided.


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