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PERFLUOROOCTYL TRIETHOXYSILANE.

Avoid CAS 51851-37-7 / BINDING

Perfluorooctyl Triethoxysilane is a fluorinated alkyl silane engineered to create hydrophobic and oleophobic surfaces. It functions in cosmetic formulations by coating pigments, enhancing their stability and facilitating uniform spread, while also having the potential to form a breathable, protective layer on the skin.

Summary

binding anticaking skin conditioning pigment coating surface modification

Science

Mechanism of Action

This ingredient operates by forming durable, self-assembled monolayers on various surfaces, thereby imparting both water-repellent (hydrophobic) and oil-repellent (oleophobic) characteristics. When incorporated into cosmetic products, it is primarily utilized to encapsulate pigments, such as those found in mineral sunscreens or colorants, ensuring their stabilization within the formula and promoting an exceptionally smooth and even distribution upon application to the skin. It can also contribute to the formation of a superficial, protective barrier on the skin's surface.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Perfluorooctyl Triethoxysilane is moisture-sensitive, reacting slowly with water or atmospheric moisture through hydrolysis and polycondensation to form a hydrophobic film. It generates heat upon contact with alkaline materials, therefore strong bases must be strictly avoided during formulation.

Conflicts

  • alcohol
  • water
  • alkalis
  • oxidizing agents
  • chemicals readily decomposed by acids (e.g., cyanides, sulfides, carbonates)
  • mild steel
  • galvanized steel
  • zinc

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

Perfluorooctyl Triethoxysilane is classified as a per- and polyfluoroalkyl substance (PFAS). The FDA acknowledges the intentional use of certain PFAS in cosmetics for properties like skin/hair conditioning and texture modification, but raises significant concerns regarding the environmental persistence, bioaccumulation in biological systems, and potential long-term health risks associated with many PFAS compounds. The Environmental Working Group (EWG) deems this ingredient unacceptable for EWG VERIFIED products, citing risks including enhanced skin absorption, moderate endocrine disruption potential, high persistence and bioaccumulation in the environment and organisms, and moderate non-reproductive organ system toxicity. GHS classifications further indicate that it causes skin irritation and serious eye irritation.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Perfluorooctyl Triethoxysilane is a PFAS compound with significant safety concerns, including documented skin and eye irritation, potential for endocrine disruption, and high persistence and bioaccumulation, making it unsuitable for precision skincare formulations.

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