Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

PERFLUOROHEXYL ETHYLPHOSPHONIC ACID.

Avoid CAS 252237-40-4 / SURFACTANT - CLEANSING

Perfluorohexyl ethylphosphonic acid is an amphiphilic molecule, characterized by a hydrophobic and oleophobic perfluorohexyl chain combined with a hydrophilic phosphonic acid group. This structure enables significant surface activity, forming self-assembled monolayers that modify surface properties. It primarily imparts water and oil repellency, enhancing chemical resistance and altering wettability.

Surface Modifier Water Repellent Oil Repellent Surfactant

Science

This ingredient functions by leveraging its amphiphilic nature to create self-assembled monolayers upon contact with surfaces. The perfluorohexyl chain contributes robust hydrophobic and oleophobic properties, while the phosphonic acid group ensures surface adherence. On skin, these monolayers form a protective, repellent barrier that effectively modifies surface wettability, provides water and oil resistance, and enhances chemical durability.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 1 – 12
0 7 14

Stability

The compound demonstrates exceptional thermal stability and effectively maintains its surface-active properties across a broad pH range, specifically from pH 1 to 12.

Conflicts

  • strong bases
  • active metals
  • strong oxidizing agents

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

GHS classifications unequivocally indicate this ingredient causes skin irritation (H315) and serious eye irritation (H319). Furthermore, it carries a potential to cause respiratory irritation (H335).


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Given explicit GHS classifications indicating high skin and eye irritation, an unreviewed CIR safety status, and a complete absence of clinical efficacy data for skin, this ingredient is not suitable for precision skincare formulations.


Related

Finding similar ingredients…


References