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Moumoujus

PENTASODIUM PENTETATE.

Avoid CAS 140-01-2 / CHELATING

Pentasodium Pentetate is a chelating agent integral to formulation stability, preventing undesirable reactions from metal ions that can compromise product integrity. This action helps to safeguard against issues like discoloration and oxidative degradation, while also enhancing the efficacy of cleansing products.

Summary

Chelating Product Stabilizer Cleansing Enhancer

Science

Mechanism of Action

Operating as a potent chelating agent, Pentasodium Pentetate targets and sequesters various heavy metal ions, including calcium, magnesium, and copper. By isolating these reactive ions, it effectively prevents them from interfering with other cosmetic ingredients, thereby safeguarding against common formulation challenges such as instability, haze, and premature oxidation. Furthermore, its chelating action improves the performance of cleansing products, especially in mineral-rich hard water environments, and helps minimize mineral deposition on skin and hair.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This ingredient is integral to formulation stability, preventing various mineral components from binding together and negatively affecting the product. It actively combats issues such as rancidity, brown-spotting, cracking, and discoloration, and provides defense against the oxidative deterioration of cosmetics and soap products.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
3%
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) Expert Panel concluded Pentasodium Pentetate is safe at current use concentrations up to 3.0%, its regulatory status outside the US is a critical consideration. As of December 1, 2023, its use in cosmetic products manufactured in the EU is prohibited due to its classification as a Carcinogenic, Mutagenic, Reprotoxic (CMR) chemical. It is also listed as 'Unacceptable' for EWG VERIFIED products. Clinical tests indicate a low risk of sensitization and comedogenicity, with dermal penetration considered negligible. However, it can be an eye irritant and may cause non-to-moderately irritating skin reactions. The FDA recognizes it as a Food Contact Substance under specific regulations (21 CFR 175.105, 176.150).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Avoid

Due to its classification as a Carcinogenic, Mutagenic, Reprotoxic (CMR) chemical and subsequent prohibition in EU cosmetics as of December 2023, Pentasodium Pentetate is an ingredient Moumoujus recommends avoiding, despite its functional benefits.

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