Science
Mechanism of Action
As a matrikine, PENTAPEPTIDE-7 functions as a cellular messenger, stimulating skin fibroblasts to rebuild the extracellular matrix and enhance the epidermal-dermal junction. This action promotes the synthesis of crucial components such as collagen types I, II, and IV, fibronectin, and glycosaminoglycans, alongside activating wound healing gene expression.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 At concentrations between 0.001% and 0.005%, PENTAPEPTIDE-7 has been shown to repair the dermal matrix and epidermal-dermal junction, leading to improvements in skin wrinkles, roughness, and thickness.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
While other pentapeptides, such as Palmitoyl Pentapeptide-4, have undergone safety assessments by the Cosmetic Ingredient Review (CIR) Expert Panel, PENTAPEPTIDE-7 has not been individually reviewed by CIR. Data regarding its SCCS and FDA status is also not available.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PENTAPEPTIDE-7 is a valuable skin-restoring peptide demonstrating efficacy in matrix repair and anti-aging at low concentrations, though further independent safety reviews are currently unavailable.
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References
Sources