Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

PENTAPEPTIDE-15.

Insufficient Data CAS - / SKIN CONDITIONING

PENTAPEPTIDE-15 is a biomimetic signaling peptide, composed of a short chain of amino acids, designed to engage with skin cells. It aims to stimulate the synthesis of crucial extracellular matrix components, such as collagen, elastin, and glycosaminoglycans, which are vital for maintaining skin structure and youthfulness.

Summary

Anti-aging Firming Wrinkle Reduction Skin Texture Improvement Hydration Support Collagen Synthesis Booster Elastin Synthesis Booster Glycosaminoglycan Synthesis Booster

Science

Mechanism of Action

Functioning as a signaling peptide, PENTAPEPTIDE-15 interacts with skin's fibroblasts to trigger specific cellular responses. This interaction is intended to upregulate the production of key structural proteins and polysaccharides—specifically collagen, elastin, and glycosaminoglycans (GAGs)—whose natural decline contributes to visible signs of aging like loss of firmness and wrinkles.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This peptide is generally more stable in acidic environments, with optimal stability for some related cyclic pentapeptides noted around pH 3.0. Formulators should carefully control pH, as both increasing pH (towards neutral/basic) and highly acidic conditions can lead to degradation. Lyophilized powder forms offer short-term temperature resistance but require careful storage to maintain stability.

Conflicts

  • Direct acids (e.g., AHAs, BHAs)
  • Retinoids
  • Strong antioxidants (e.g., high concentrations of Vitamin C)
  • Excessive fragrance
  • Alcohol

Safety

Safety Profile

CIR Status
Safe as used
Max tested
0.0035%
Sensitization risk Low

While specific safety data for PENTAPEPTIDE-15 is not explicitly detailed, the CIR Expert Panel has concluded that related pentapeptides (e.g., Myristoyl Pentapeptide-4, Palmitoyl Pentapeptide-4, and Pentapeptide-4) are safe for use in cosmetics. The maximum use concentration for Pentapeptide-4 in leave-on products was reported as 0.0035%. Peptides are broadly considered safe in skincare, being fundamental building blocks of proteins, and typically present a low risk of serious safety concerns.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

PENTAPEPTIDE-15 presents as a theoretical stimulator of key skin components like collagen and elastin; however, specific clinical efficacy data for this exact peptide is not provided.

Related

Similar Ingredients

Finding similar ingredients…