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PENTAMETHYL-SPIROBICYCLOHEPTANE-DIOXANE.

Avoid CAS 121251-67-0 / PERFUMING

Pentamethyl-Spirobicycloheptane-Dioxane is a synthetic aromatic compound primarily utilized in cosmetic formulations for its distinct perfuming qualities. Available research does not indicate any direct beneficial effects or efficacy on skin health.

perfuming

Science

The precise mechanism by which Pentamethyl-Spirobicycloheptane-Dioxane interacts with skin at a biological level for therapeutic effect is not currently elucidated, as its function is predominantly sensory.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Current research data provides no information regarding the dusting potential of Pentamethyl-Spirobicycloheptane-Dioxane in cosmetic formulations.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

To maintain optimal integrity, Pentamethyl-Spirobicycloheptane-Dioxane should be stored in its original, tightly sealed container at a maximum temperature of 25°C. Prolonged exposure to light, heat, and air should be prevented.

Conflicts

  • strong oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Moderate

European regulatory information classifies Pentamethyl-Spirobicycloheptane-Dioxane as an irritant (Xi), specifically noting its irritating effects on the skin (R 38). Dermal contact may result in harm, evidenced by an LD50 Dermal Rabbit > 2000 mg/kg. Consequently, direct contact with the product must be avoided. Its safety profile for use during pregnancy has not been established. Additionally, this ingredient poses a significant environmental risk, being toxic to aquatic organisms with potential for long-term adverse effects (R 51/53, H411).


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Avoid

Given its classification as a skin irritant and the complete absence of clinical data demonstrating skin benefits or efficacy, Pentamethyl-Spirobicycloheptane-Dioxane is not recommended for precision skincare formulations.


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