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Moumoujus

PENTAERYTHRITYL TETRAMERCAPTOPROPIONATE.

Avoid CAS 7575-23-7 / FILM FORMING

Pentaerythrityl Tetramercaptopropionate is primarily employed as a robust crosslinking agent, forming highly durable polymeric networks in industrial applications. Within cosmetic formulations, its presence is documented for film-forming characteristics, yet it is not recognized as a primary active ingredient for direct skin benefits.

Summary

Crosslinking agent Film-forming agent

Science

Mechanism of Action

This compound functions by engaging its numerous mercapto (thiol) groups in efficient thiol-ene or thiol-yne 'click' reactions. These reactions facilitate the creation of extensively crosslinked polymer structures, imparting enhanced mechanical strength and chemical resistance to materials. When applied topically, this mechanism contributes to the formation of a surface film.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Pentaerythrityl Tetramercaptopropionate is not an ingredient typically 'dusted' for perceived skin benefits, as its reported cosmetic use is limited to film formation and lacks evidence of active dermatological efficacy.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The compound demonstrates chemical stability under standard ambient storage conditions at room temperature.

Conflicts

  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed Pentaerythrityl Tetramercaptopropionate; while related pentaerythrityl tetraester compounds have been assessed as safe, this ingredient's distinct chemical structure, a tetramercaptopropionate, differentiates it. Hazard statements indicate potential harm if swallowed (H302), a notable risk of causing allergic skin reactions (H317), potential respiratory irritation (H335), and possible organ damage (H371). Furthermore, it is classified as very toxic to aquatic life with long-lasting effects (H410). The FDA Global Substance Registration System (GSRS) lists a UNII for the substance (6M5413VH6N), noting its approval is not for a standalone chemical but rather as a component within products covered by group standards.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to its documented high irritancy, potential for allergic skin reactions, lack of established skin benefits, and predominant industrial applications, this ingredient is unsuitable for inclusion in precision skincare formulations.

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References

Sources