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Moumoujus

PENTADECYL ALCOHOL.

Insufficient Data CAS 629-76-5 / EMULSION STABILISING, SKIN CONDITIONING - EMOLLIENT

Pentadecyl Alcohol is a long-chain fatty alcohol primarily known for its emollient properties, creating a protective barrier to minimize moisture loss and improve skin texture. It also serves as a valuable formulation aid, enhancing product viscosity and stability.

Summary

Emollient Emulsion Stabilizer Viscosity Controller

Science

Mechanism of Action

On the skin, Pentadecyl Alcohol acts as an emollient by forming a lipidic layer that reduces trans-epidermal water loss, thereby enhancing skin hydration and smoothness. Within cosmetic formulations, it contributes to viscosity control and maintains emulsion homogeneity.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Exhibits a Minimum Inhibitory Concentration (MIC) of 0.78 μg/mL against Cutibacterium acnes (formerly Propionibacterium acnes).
  2. 02 Achieves a Minimum Bactericidal Concentration (MBC) of 1.56 μg/mL against Cutibacterium acnes.
  3. 03 Demonstrates a Minimum Inhibitory Concentration (MIC) of 6.25 μg/mL against Brevibacterium ammoniagenes.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Pentadecyl Alcohol generally exhibits chemical stability. However, it can react with strong reducing agents, alkali metals, and nitrides, potentially generating flammable or toxic gases. It also forms esters when reacted with oxoacids and carboxylic acids, and is susceptible to oxidation into aldehydes or ketones. Furthermore, it may initiate the polymerization of isocyanates and epoxides.

Conflicts

  • Alkali metals
  • Nitrides
  • Strong reducing agents
  • Oxoacids
  • Carboxylic acids
  • Oxidizing agents
  • Isocyanates
  • Epoxides
  • EPDM rubber (for industrial handling)

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Moderate

While listed in the FDA Global Substance Registration System (GSRS), Pentadecyl Alcohol currently lacks comprehensive safety assessments from organizations like the Cosmetic Ingredient Review (CIR) or Scientific Committee on Consumer Safety (SCCS). It generally exhibits low systemic toxicity via oral, dermal, and inhalation routes. However, there is a potential for slight to moderate irritation to ocular and dermal tissues, and prolonged exposure to undiluted forms can lead to epidermal defatting.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Pentadecyl Alcohol effectively functions as an emollient and cosmetic formulation aid, yet more comprehensive safety and efficacy assessments are needed for a definitive dermatological profile.

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